protein.neoamorfic.ai
NeoAmorficX-40

Stage 1 Batch Static Showcase

MAP3K1

Real static evidence-chain result for run MAP3K1-demo. This page uses a real local AlphaFold/AFDB-compatible structure file, computes pLDDT/range metrics from that file, renders parsed coordinates, and exposes downloadable artifacts. It is not yet a live browser-submitted run.

Status
REAL_STRUCTURE_REAL_COMPUTED_METRICS_STATIC_BATCH_SHOWCASE
Static batch showcase: this result is one row from a real computed batch-demo panel. It is not yet a live user-submitted batch run.
Accession
Q13233
Triage Score
high priority
Recommended Action
open_first
Numeric score
80
SourceStructureMetricsReview CardGoverned QCDownloads

Source Provenance

This panel proves what structure was used and where it came from.

Database
AlphaFold Protein Structure Database / AFDB-compatible source
Accession
Q13233 / AF-Q13233-F1
Source URL
https://alphafold.ebi.ac.uk/entry/Q13233
Structure file URL
/structures/batch-demo/AF-Q13233-F1-model_v6.pdb
Fetched file
AF-Q13233-F1-model_v6.pdb
File SHA-256
f967885044bd3d92562245232397da336d63adbf452261b7bcfd2de3eb338c0d
Category
kinase / structural triage

3D Structure and Confidence

This viewer renders real parsed PDB coordinates from the local structure file.

Loading structure…
Loading local MAP3K1 structure…

Viewer status

loading

Display legend

Very high confidence
Confident
Low confidence
Very low confidence
Purple overlay: flagged example ranges

Display mode

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Flagged ranges

Demo note: this is a direct browser projection of real PDB coordinates. Production runs can later replace it with a full Mol* molecular viewer.

Confidence Summary and Flagged Ranges

These values are computed from the local PDB B-factor/pLDDT fields.

CA residues
1512
pLDDT < 70
0.564153
pLDDT < 50
0.490079
Mean pLDDT
58.747
Contact density
low / extended or uncertain packing
ChainStartEndLengthMean confidenceMin confidence
A870117830931.7724.47
A129829834.5725.08
A4975485238.725.45
A4014404042.1227.73
A5996272937.2727.05

Scientist Review Card

This card is generated from the computed static-showcase metrics and remains triage-only.

Reasons

  • • Large low-confidence fraction: 0.564 of residues are below pLDDT 70.
  • • Substantial very-low-confidence fraction: 0.490 of residues are below pLDDT 50.
  • • Longest low-confidence segment spans chain A residues 870–1178 (309 residues).
  • • Low C-alpha contact density suggests an extended, uncertain, or weakly packed predicted arrangement.

Inspection checklist

  • • Inspect chain A residues 870–1178 first.
  • • Compare high-confidence regions against low-confidence or extended regions.
  • • Use this card to prioritize manual structural review, not to infer mechanism.
  • • Review source file hash and downloads before reusing the result.

Warnings

  • • Structural triage only.
  • • No biological validation, binding prediction, stability prediction, inhibitor analysis, clinical guidance, or pharma-grade decision support.

Governed QC Review

This section shows the Stage 1 V3.1 governed validation gate summary, not a fresh browser-page X-40 call.

Status
validation_gate_summary_not_live_per_result_call
Profile
biomol_qc_review
Model
gpt-4.1-2025-04-14
Policy reason
BIOMOL_QC_REVIEW_CONTRACT
Released output mode
biomol_qc_review_contract_json
100-card parse success
100/100
Usefulness
3.95
Clarity
4.96
Overclaim risk
0.3
Note
This page shows the Stage 1 V3.1 governed validation gate summary. It is not a fresh live X-40 call for this browser page.

Download Evidence Bundle

These downloads are real static-showcase artifacts generated from the local structure file.

JSONMetrics CSVRanges CSVCard MDManifestSHA-256