{
  "domain_trends": [
    {
      "domain": "1e8rA00",
      "n": 25,
      "status": "DOMAIN_TREND_SIGNAL_PRESENT",
      "temps": [
        320,
        348,
        379,
        413,
        450
      ],
      "trend_hits": 8
    },
    {
      "domain": "1el6A01",
      "n": 24,
      "status": "DOMAIN_TREND_SIGNAL_PRESENT",
      "temps": [
        320,
        348,
        379,
        413,
        450
      ],
      "trend_hits": 10
    },
    {
      "domain": "1ha8A00",
      "n": 25,
      "status": "DOMAIN_TREND_SIGNAL_PRESENT",
      "temps": [
        320,
        348,
        379,
        413,
        450
      ],
      "trend_hits": 8
    },
    {
      "domain": "1kloA01",
      "n": 25,
      "status": "DOMAIN_TREND_SIGNAL_PRESENT",
      "temps": [
        320,
        348,
        379,
        413,
        450
      ],
      "trend_hits": 9
    }
  ],
  "governed_qc": {
    "claim_boundary": "Free Stage 2 V2 is a governed evidence extraction and sanity-reporting tool for real existing MD trajectories.",
    "not_claimed": [
      "FlexSense classification",
      "protein stability prediction",
      "biological mechanism claim",
      "pharma-grade decision system"
    ],
    "status": "stage2_v2_internal_public_alpha_candidate_after_review"
  },
  "metric_policy": {
    "claim_safe_metrics": [
      "MSE_mean",
      "Phi_abs_mean",
      "S_mean",
      "attractor_curvature_mean",
      "attractor_radius_mean",
      "coupling_entropy_flow_mean",
      "coupling_resonance_mean",
      "dS_abs_mean",
      "kappa_abs_mean",
      "lyapunov_mean",
      "resonance_mean"
    ],
    "diagnostic_log_only_metrics": [
      "coherence_mean",
      "coupling_coherence_mean",
      "coupling_lyapunov_sync_mean",
      "coupling_strength"
    ]
  },
  "mode": "stage2_known_md_static_showcase",
  "overall_trend_hits": [
    {
      "metric": "Phi_abs_mean",
      "r": 0.9085275619316816,
      "slope": 0.0035543625793697116
    },
    {
      "metric": "S_mean",
      "r": 0.6377768650213396,
      "slope": 0.003429524825793695
    },
    {
      "metric": "attractor_curvature_mean",
      "r": -0.4402977476668915,
      "slope": -0.0006756887208837139
    },
    {
      "metric": "attractor_radius_mean",
      "r": -0.5627693605077898,
      "slope": -0.0009542881564611367
    },
    {
      "metric": "coupling_entropy_flow_mean",
      "r": -0.32934081359634576,
      "slope": -0.0006706618143162654
    },
    {
      "metric": "coupling_resonance_mean",
      "r": 0.4439459664463893,
      "slope": 0.00023026230186745268
    },
    {
      "metric": "resonance_mean",
      "r": 0.892218813794981,
      "slope": 0.0042396570483085394
    }
  ],
  "run_id": "known-md-demo",
  "scientist_card": {
    "inspection_checklist": [
      "Review the claim-safe metrics separately from diagnostic/log-only metrics.",
      "Inspect per-domain trend consistency before drawing conclusions.",
      "Treat this as governed MD evidence extraction, not a stability or mechanism prediction.",
      "Request raw trajectory-level package before using for institutional validation."
    ],
    "main_interpretation": "Stage 2 V2 found claim-safe trend signals across real known-MD evidence cases under thermal-stress conditions.",
    "reasons": [
      "The run summarized 99 mdCATH-derived evidence cases.",
      "All four held-out domains showed trend signal presence.",
      "Seven claim-safe metrics showed overall trend hits.",
      "Metric policy separates claim-safe evidence from diagnostic/log-only metrics."
    ],
    "recommended_action": "review_as_stage2_known_md_evidence_showcase",
    "warnings": [
      "Not protein-stability prediction.",
      "Not biological mechanism proof.",
      "Not FlexSense classification.",
      "Not binding prediction.",
      "Not pharma-grade decision support.",
      "Raw trajectories are not included in this static website showcase."
    ]
  },
  "source": {
    "claim_boundary": "Governed evidence extraction and sanity reporting from real existing MD trajectories; not protein-stability prediction or biological mechanism proof.",
    "evidence_basis": "mdCATH-derived known-MD evidence cases previously processed by the Stage 2 V2 engine",
    "pipeline": "Known-MD QEIv15/X-40 Stage 2 V2",
    "raw_trajectory_status": "Raw trajectories are not bundled in this website static showcase."
  },
  "status": "REAL_KNOWN_MD_EVIDENCE_STATIC_SHOWCASE_FROM_STAGE2_V2",
  "summary": {
    "domains": 4,
    "evidence_cards": 99,
    "held_out_pass_count": 4,
    "held_out_pass_rate": 1.0,
    "held_out_total": 4,
    "local_biomol_known_md_cases": 11,
    "local_biomol_known_md_success_rate": 1.0,
    "mdcath_evidence_cases": 99,
    "overall_claim_safe_trend_hits": 7
  }
}