# Biomol Evidence Alpha — Final Researcher-Alpha Brief

## Status

Biomol Evidence Alpha is in controlled researcher-alpha preparation.

The platform supports protected pilot keys, first-use activation, quotas, counters, protected results, protected artifact downloads, Structural Triage, MD Evidence, Pilot Access Status, and Integrated Evidence Dossier planning.

## Active functions

### Structural Triage

Use for large protein panels.

Best suited for:

- protein target panels
- UniProt accession lists
- first-pass prioritization
- structural review triage
- downloadable evidence packages

### MD Evidence

Use for selected compatible trajectory packages.

Best suited for:

- topology + trajectory evidence review
- parser status
- file identity
- RMSD/RMSF/radius-of-gyration summaries
- protected evidence bundles

### Integrated Evidence Dossier

Planned synthesis layer.

It will combine Structural Triage and MD Evidence into one target-level evidence dossier.

## Pilot key policy

Pilot key 01 is internal validation only.

External reviewers should receive one unused key each from the external key pool.

Standard pilot:

- 20 jobs
- 30 days from first registered job
- 1,000 Structural Triage target quota
- 500 MB MD Evidence upload quota

## Reviewer workflow

1. Receive key.
2. Check Pilot Access Status.
3. Run Structural Triage or MD Evidence.
4. Review protected result.
5. Download evidence bundle.
6. Submit evaluation feedback.

## Current exposure policy

Do not distribute keys broadly.

Use only guided private researcher-alpha preparation until:

- result-page visual polish is complete
- white paper is finalized
- one external non-AdK trajectory has been run or prepared
- reviewer feedback form is ready


## External non-AdK validation

MD Evidence has passed an external non-AdK NhaA trajectory gate.

Summary:

- System: NhaA membrane protein
- Format path: GRO + XTC
- Frames analyzed: 20
- Atoms: 60,702
- Residues: 1,314
- Protein selection atoms: 11,624
- Result status: complete
- Parse status: parsed
- MD metrics computed: true

This confirms that MD Evidence is not limited to the earlier AdK validation path.